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男性死后精子利用进行精子库存储:患者选择的分析。

Posthumous sperm utilization in men presenting for sperm banking: an analysis of patient choice.

机构信息

Scott Department of Urology, Baylor College of Medicine, Houston, TX 77030, USA.

出版信息

Andrology. 2013 Mar;1(2):251-5. doi: 10.1111/j.2047-2927.2012.00027.x. Epub 2013 Jan 13.

DOI:10.1111/j.2047-2927.2012.00027.x
PMID:23315967
Abstract

The question remains as to whether or not men would agree to posthumous sperm use for pregnancy initiation. Often, these individuals' lives are suddenly interrupted and prior consent is rarely given. Therefore, post-mortem retrieval or use of these spermatozoa remains controversial and the incidence of consent for post-mortem sperm use is not clear. Men who bank spermatozoa, however, represent a cohort that can be examined for frequency of consent for post-mortem sperm use. We performed a retrospective chart review for 364 patients presenting for sperm banking at a single institution from 2009 to 2011. Banked specimens represented either ejaculated or surgically retrieved spermatozoa. Demographic information was obtained for each patient and men were grouped by reason for sperm banking, relationship and paternity status, and consent for post-mortem sperm use. The frequency of post-mortem consent was determined within each group. Men were grouped based on reason for banking, including infertility ('Infertility') or malignancy prior to treatment ('Cancer'). Mean ± SD age of the infertility and cancer groups were 40.1 ± 9.9 years and 27.1 ± 9.6 years, respectively. Of the 364 men, 85.9% provided consent for post-mortem sperm use. In the infertility group, 87.4% of men consented. Of these, 92.9% men in a relationship and 62.5% single men consented. Regarding paternity status, 64.7% men with and 56.6% men without children consented. Within the cancer cohort, 83.8% men consented. Of men <18 years old and ≥18 years old, 65.2 and 85.8% consented, respectively. Relationship status yielded 93.2% men in relationships and 79.4% single men consenting. Paternity status in the cancer group yielded 95.8% with and 82.4% men without children consenting. In summary, most men presenting for sperm banking provided consent for post-mortem sperm use, irrespective of reason for banking. Men who are in a relationship or who are fathers were more likely to agree to post-mortem sperm use.

摘要

对于男性是否会同意死后使用精子进行妊娠启动,问题仍然存在。通常,这些人的生命会突然中断,很少事先同意。因此,死后获取或使用这些精子仍然存在争议,死后使用精子的同意率尚不清楚。然而,储存精子的男性可以作为一个队列进行检查,以确定他们同意死后使用精子的频率。我们对 2009 年至 2011 年在一家机构进行精子储存的 364 名患者进行了回顾性图表审查。储存的样本代表射出的或手术获取的精子。我们获得了每位患者的人口统计学信息,并根据精子储存的原因、关系和父亲身份以及死后精子使用的同意情况对男性进行分组。在每个组中确定了死后同意的频率。男性根据储存精子的原因进行分组,包括不孕(“不孕”)或治疗前的恶性肿瘤(“癌症”)。不孕和癌症组的平均年龄±标准差分别为 40.1±9.9 岁和 27.1±9.6 岁。在 364 名男性中,85.9%的人同意死后使用精子。在不孕组中,87.4%的男性同意。其中,92.9%的有伴侣男性和 62.5%的单身男性同意。关于父亲身份,64.7%有孩子的男性和 56.6%没有孩子的男性同意。在癌症队列中,83.8%的男性同意。18 岁以下和 18 岁以上的男性分别有 65.2%和 85.8%同意。关系状况导致 93.2%的有伴侣男性和 79.4%的单身男性同意。在癌症组中,有孩子的男性和没有孩子的男性分别有 95.8%和 82.4%同意。总之,大多数来储存精子的男性无论储存精子的原因如何,都同意死后使用精子。有伴侣或有孩子的男性更有可能同意死后使用精子。

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