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二尖瓣手术现在可以常规地通过内镜进行。

Mitral valve surgery can now routinely be performed endoscopically.

作者信息

Casselman Filip P, Van Slycke Sam, Wellens Francis, De Geest Raphael, Degrieck Ivan, Van Praet Frank, Vermeulen Yvette, Vanermen Hugo

机构信息

Department of Cardiovascular and Thoracic Surgery, OLV Clinic, Moorselbaan 164, 9300 Aalst, Belgium.

出版信息

Circulation. 2003 Sep 9;108 Suppl 1:II48-54. doi: 10.1161/01.cir.0000087391.49121.ce.

Abstract

BACKGROUND

There is an increasing interest in minimally invasive cardiac surgery.

METHODS AND RESULTS

Since February 1, 1997 till April 1, 2002, 306 patients underwent endoscopic mitral valve surgery (226 repair, MVP; 80 replacement, MVR). Predominant valve pathology was degenerative in MVP (83.6%) and rheumatic in MVR (65%). Mean age was 61.5+/-12.9 years. Median preoperative functional class (MVP+MVR) and mitral regurgitation (MVP) were II and 4+. Statistical analysis included Kaplan-Meier and Cox regression methods. Mean follow-up was 19.6+/-17.3 months and complete. The procedure was successfully performed in all but 6 patients. Hospital mortality included 3 patients (1%) and was technology related in one. Postoperative morbidity included aggressive re-exploration (8.5%), new onset atrial fibrillation (17.0%), and pacemaker implantation (2.3%). There were 1 early and 10 late reoperations, 5 of which were because of endocarditis. Freedom from mitral valve reoperation at 4 years was 91+/-3.5%. No risk factors for reoperation could be detected. Echocardiographic follow-up showed a median degree of mitral regurgitation (MVP) of 0 and a small paravalvular leak in four patients (MVR). Ninety-four percent of the patients reported no or mild postoperative pain and 99.3% felt they had an esthetically pleasing scar. Ninety-three percent would choose the same procedure again and 46.1% were back at work within 4 weeks.

CONCLUSIONS

Endoscopic mitral valve surgery can be performed safely but definitely requires a learning curve. Good results and a high patient satisfaction are guaranteed. It is now our exclusive approach for isolated atrioventricular valve disease.

摘要

背景

微创心脏手术越来越受到关注。

方法与结果

自1997年2月1日至2002年4月1日,306例患者接受了内镜二尖瓣手术(226例修复,二尖瓣修复术;80例置换,二尖瓣置换术)。二尖瓣修复术(MVP)的主要瓣膜病变为退行性变(83.6%),二尖瓣置换术(MVR)的主要瓣膜病变为风湿性(65%)。平均年龄为61.5±12.9岁。术前功能分级(MVP+MVR)和二尖瓣反流(MVP)的中位数分别为Ⅱ级和4+级。统计分析采用Kaplan-Meier法和Cox回归法。平均随访时间为19.6±17.3个月,随访完整。除6例患者外,所有手术均成功完成。住院死亡率为3例(1%),其中1例与技术相关。术后并发症包括积极再次手术探查(8.5%)、新发房颤(17.0%)和起搏器植入(2.3%)。有1例早期再次手术和10例晚期再次手术,其中5例是由于心内膜炎。4年时二尖瓣再次手术的无复发生存率为91±3.5%。未发现再次手术的危险因素。超声心动图随访显示二尖瓣反流(MVP)的中位数为0级,4例患者(MVR)有小的瓣周漏。94%的患者报告术后无疼痛或轻度疼痛,99.3%的患者认为瘢痕美观。93%的患者会再次选择相同的手术,46.1%的患者在4周内恢复工作。

结论

内镜二尖瓣手术可以安全进行,但肯定需要一个学习曲线。可保证良好的效果和较高的患者满意度。目前,它是我们治疗单纯房室瓣疾病的唯一方法。

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