Sorgdrager B, Pal T M, De Monchy J G, Togtema H R, Kolk J J
Department of Allergology University Hospital, Groningen, The Netherlands.
Med Lav. 1992 Sep-Oct;83(5):435-7.
We carried out a nested case-control study in an aluminium producing plant, using the results of pre-employment examination to identify workers with an increased risk of developing work-related obstructive respiratory symptoms. Cases (n=49) are those who had become unable to work because of work-related respiratory disease. They were compared with 49 matched controls. Pre-employment eosinophil count was strongly related to the occurrence of work-related obstructive respiratory disease. This finding is interesting in the light of a possible pathogenesis.
我们在一家铝生产厂开展了一项巢式病例对照研究，利用入职前检查结果来识别患工作相关阻塞性呼吸道症状风险增加的工人。病例组（n = 49）为那些因工作相关呼吸道疾病而无法工作的人。将他们与49名匹配的对照组进行比较。入职前嗜酸性粒细胞计数与工作相关阻塞性呼吸道疾病的发生密切相关。鉴于可能的发病机制，这一发现很有意思。
