Carta P, Boscaro G, Mantovano S, Papi G, D'Ambrosio P, Cherchi P
Instituto di Medicina del Lavoro, Università di Cagliari.
Med Lav. 1992 Sep-Oct;83(5):438-44.
The paper reports the results of a longitudinal study of 1478 workers in the primary aluminium industry in Italy (aluminium reduction with the pre-baked anode process) covering the prevalence and incidence of chronic obstructive lung disease, chronic bronchitis and bronchial asthma, and analysis of lung function deterioration over time (annual decline in FEV1) in relation to occupational exposure and individual non-occupational features. The incidence of respiratory symptoms of chronic cough and expectoration was significantly higher among electrolytic shop workers, in whom the annual decline in FEV1 was also significantly greater. In this group the incidence and prevalence of asthmatic manifestations was particularly high compared to casting and workshop workers. Asthmatic symptoms showed a short latency period related to exposure in potrooms and seems to be characterized by a marked deterioration in lung function over time even after withdrawal from exposure.
该论文报告了一项针对意大利原铝行业1478名工人的纵向研究结果(采用预焙阳极工艺进行铝还原),涵盖慢性阻塞性肺疾病、慢性支气管炎和支气管哮喘的患病率和发病率,以及与职业暴露和个体非职业特征相关的肺功能随时间的恶化分析(FEV1的年下降率)。电解车间工人慢性咳嗽和咳痰等呼吸道症状的发病率显著更高,他们的FEV1年下降率也显著更大。与铸造和车间工人相比,该组哮喘表现的发病率和患病率特别高。哮喘症状与在电解车间的暴露相关的潜伏期较短,并且似乎其特征是即使在停止暴露后,肺功能也会随时间显著恶化。