Kizilay Ahmet, Erdem Tamer, Mizrak Bülent, Bayindir Tuba, Ozturan Orhan
Department of Otolaryngology, Medicine Faculty of Inönü University, Malatya, Turkey.
Kulak Burun Bogaz Ihtis Derg. 2003 May;10(5):213-5.
Necrotizing sialometaplasia is a benign, reactive, and self-limiting inflammatory disorder with clinical and histologic features resembling carcinoma. A fifty-eight-year-old woman presented with a firm submucosal mass on the right side of the upper lip, measuring 0.5 cm. Histopathologic examination of the incisional biopsy specimen was reported as adenoid cystic carcinoma, resulting in removal of the mass with a large excision and reconstruction of the primary site. However, final histopathologic diagnosis of the excised mass was necrotizing sialometaplasia. No recurrences occurred during a three-year follow-up. This report draws attention to the difficulty in distinguishing between necrotizing sialometaplasia and adenoid cystic carcinoma.
坏死性涎腺化生是一种良性、反应性且自限性的炎症性疾病，其临床和组织学特征类似于癌。一名58岁女性上唇右侧出现一个0.5厘米的坚实黏膜下肿物。切开活检标本的组织病理学检查报告为腺样囊性癌，遂行肿物广泛切除及原发部位重建。然而，切除肿物的最终组织病理学诊断为坏死性涎腺化生。在三年随访期间未出现复发。本报告提请注意坏死性涎腺化生与腺样囊性癌鉴别的困难。
