Alfuhaid Turki R, Rosen Barry P, Wilson Stephanie R
Department of Medical Imaging, University Health Network, University of Toronto, Ontario, Canada.
Ultrasound Q. 2003 Mar;19(1):13-26. doi: 10.1097/00013644-200303000-00003.
The biologic, behavioral, and pathologic features of low-malignant-potential (LMP) tumor of the ovary are distinct from their invasive counterpart. LMP tumors affect patients at a younger age and have a much better 5- and 20-year survival rate compared with invasive ovarian malignancy. The authors retrospectively reviewed the records and sonograms of 41 patients (51 masses) with LMP tumor of the ovary. They demonstrated a wide variety of morphologies on the presentation sonograms with six masses favored to be benign, four indeterminate, 18 likely malignant, and 23 clearly malignant. Eighteen of 51 masses (35.3%) had a unique appearance-a cyst within the ovary of small to medium size with vascular mural nodularity and preserved surrounding ovarian parenchyma. Low-level echoes within the cystic components of the mass, reminiscent of typical endometrioma, were present in 19 of 51 masses (37.2%). Peritoneal dissemination was present in six patients at presentation, all! whom were alive at follow-up between 45 and 120 months. The authors think that many LMP tumors may be recognized and treated while they are still small. Ovary-sparing surgery may preserve patient fertility. LMP tumors may present initially with a benign morphology, although temporal evolution tends to show more suspicious features. Because these tumors may also appear frankly malignant or show peritoneal dissemination, the possibility of LMP tumor must be considered in light of their much better prognosis compared with invasive ovarian malignancy.
卵巢低恶性潜能（LMP）肿瘤的生物学、行为学和病理学特征与其侵袭性对应物不同。LMP肿瘤影响的患者年龄较轻，与侵袭性卵巢恶性肿瘤相比，其5年和20年生存率要好得多。作者回顾性分析了41例卵巢LMP肿瘤患者（51个肿块）的记录和超声图像。他们在超声图像上展示了多种形态，其中6个肿块倾向于良性，4个不确定，18个可能恶性，23个明确恶性。51个肿块中有18个（35.3%）有独特表现——卵巢内中小尺寸囊肿，伴有血管壁结节，周围卵巢实质保留。51个肿块中有19个（37.2%）在肿块的囊性成分内有低回声，类似于典型的子宫内膜异位症。6例患者在初诊时出现腹膜播散，所有这些患者在45至120个月的随访中均存活。作者认为许多LMP肿瘤在仍较小的时候就可以被识别和治疗。保留卵巢的手术可以保留患者的生育能力。LMP肿瘤最初可能表现为良性形态，尽管随着时间推移往往会出现更多可疑特征。由于这些肿瘤也可能表现为明显恶性或出现腹膜播散，鉴于其预后比侵袭性卵巢恶性肿瘤好得多，必须考虑LMP肿瘤的可能性。
