Sjögren B, Elinder C G
Department of Occupational Medicine, National Institute of Occupational Health, Solna, Sweden.
Med Lav. 1992 Sep-Oct;83(5):484-8.
Exposure to high levels of aluminium can affect the human central nervous system. Abnormalities of psychomotor function have been observed among haemodialysis patients with mean aluminium concentrations in serum of about 60 micrograms/l. According to our own data this corresponds to a urinary level of about 330 micrograms Al/l in aluminium-exposed welders without kidney failure. This post-shift urinary level of aluminium is estimated to be attained after 40 years of exposure to a welding fumes at an environmental concentration of approximately 1.6 mg/m3 of aluminium. An increased prevalence of effects on the nervous system was observed among welders exposed to aluminium fumes for more than 13 years. This finding supports the concept of cumulative toxicity due to aluminium exposure. On the basis of these observation, we suggest that the level of aluminium in welding fumes should not exceed 1 mg/m3.
接触高浓度铝会影响人体中枢神经系统。在血清平均铝浓度约为60微克/升的血液透析患者中，已观察到精神运动功能异常。根据我们自己的数据，这相当于未患肾衰竭的铝接触焊工的尿铝水平约为330微克/升。估计在环境铝浓度约为1.6毫克/立方米的焊接烟雾中接触40年后，会达到这种下班后的尿铝水平。在接触铝烟雾超过13年的焊工中，观察到对神经系统影响的患病率增加。这一发现支持了铝接触导致累积毒性的概念。基于这些观察结果，我们建议焊接烟雾中的铝含量不应超过1毫克/立方米。
