对患有贝克威思-维德曼综合征或孤立性半身肥大的儿童进行血清甲胎蛋白筛查以诊断肝母细胞瘤。
Serum alpha-fetoprotein screening for hepatoblastoma in children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia.
作者信息
Clericuzio Carol L, Chen Emily, McNeil Dawn Elizabeth, O'Connor Timothy, Zackai Elaine H, Medne Livija, Tomlinson Gail, DeBaun Michael
机构信息
Department of Pediatrics, University of New Mexico, ACC-3, Albuquerque, NM 87131, USA.
出版信息
J Pediatr. 2003 Aug;143(2):270-2. doi: 10.1067/S0022-3476(03)00306-8.
An elevated risk of hepatoblastoma for children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia is well established. We describe five children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia for whom serial serum alpha-fetoprotein screening, usually in combination with abdominal ultrasound, led to early detection of hepatoblastoma.
患有贝克威思-维德曼综合征或孤立性半身肥大的儿童患肝母细胞瘤的风险升高已得到充分证实。我们描述了5例患有贝克威思-维德曼综合征或孤立性半身肥大的儿童，他们通过连续血清甲胎蛋白筛查（通常结合腹部超声检查），得以早期发现肝母细胞瘤。
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