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尸检中有毒物质/滥用药物存在情况的五年审计。

Five years audit for presence of toxic agents/drug of abuse at autopsy.

作者信息

Ali S Muhammad Aijaz, Khalil Inayatur-ur-Rehman, Saeed Ahmed, Hussain Zahid

机构信息

Department of Forensic Medicine, Khyber Medical, College Peshawar.

出版信息

J Coll Physicians Surg Pak. 2003 Sep;13(9):519-21.

Abstract

OBJECTIVE

To know the frequency of fatal poisoning in Peshawar regarding the toxic agents mostly involved and yearwise percentage. To know the age group and the gender that is most vulnerable to fatal poisoning.

DESIGN

Non-interventional (descriptive) type.

PLACE AND DURATION OF STUDY

This study was conducted over a period of five years (1997-2001) at Forensic Medicine Department, Khyber Medical College, Peshawar.

METHODOLOGY

The study included 3508 autopsies conducted at Khyber Medical College, Peshawar. Out of these, 52 cases were those caused by fatal poisoning. These were analyzed according to age, gender and the toxic agent involved. t-test was applied as the test of significance.

RESULTS

Poisoning was the cause of death in 1.48% of the total autopsies conducted during the five years. Males were more involved than the females, 90.38 %. Suicidal poisoning was present in 17.30% of the total cases and accidental poisoning was found in 80.72% cases, while homicidal cases were 1.29% only. Diacetylmorphine (heroin) was the most commonly involved agent, 65.38 %, of the total cases. The incidence of poisoning was more during the third and fourth decades of life.

CONCLUSION

Diacetylmorphine (heroin) was the main causative agent involved in young males due to accidental over- dosage. Accidental and suicidal deaths should not be considered as inevitable. More elaborative studies are required in this area of recent research to adopt appropriate and adequate measures to save precious lives.

摘要

目的

了解白沙瓦地区致命中毒事件中主要涉及的有毒物质的频率及逐年百分比。了解最易发生致命中毒的年龄组和性别。

设计

非干预性(描述性)类型。

研究地点和时间

本研究在白沙瓦市开伯尔医学院法医学系进行,为期五年(1997 - 2001年)。

方法

该研究纳入了白沙瓦市开伯尔医学院进行的3508例尸检。其中,52例是由致命中毒导致的。对这些案例按照年龄、性别和涉及的有毒物质进行了分析。采用t检验作为显著性检验。

结果

在五年期间进行的全部尸检中,中毒是1.48%的死亡原因。男性比女性更易涉及,占90.38%。自杀中毒占总案例的17.30%,意外中毒占80.72%,而他杀案例仅占1.29%。二乙酰吗啡(海洛因)是最常涉及的物质,占总案例的65.38%。中毒发生率在生命的第三个和第四个十年期间更高。

结论

二乙酰吗啡(海洛因)是年轻男性因意外过量服用而导致中毒的主要致病因素。不应将意外和自杀死亡视为不可避免。在这一最新研究领域需要进行更详尽的研究,以采取适当和充分的措施挽救宝贵生命。

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