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乌干达坎帕拉两家医院的急性中毒事件。

Acute poisoning at two hospitals in Kampala-Uganda.

作者信息

Malangu N

机构信息

Faculty of Medicine, School of Public Health, University of Limpopo (Medunsa Campus), Pretoria, South Africa.

出版信息

J Forensic Leg Med. 2008 Nov;15(8):489-92. doi: 10.1016/j.jflm.2008.04.003. Epub 2008 Jun 16.

Abstract

BACKGROUND

The aim of this study was to characterize acute poisoning cases admitted to two hospitals in Kampala, Uganda.

STUDY DESIGN

All cases admitted to the two hospitals, from January 2005 to June 2005, were evaluated retrospectively. Data obtained from the hospital medical records included the following: demographic characteristics, toxic agents, length of stay, circumstances of poisoning, and mortality information on the victims.

RESULTS

Of the total 276 patients admitted for treatment, whose mean age was 26.6 (+/-12.2) years, 71.0 % were males. The age category of 20-29 years old most affected (42.8%), while only 5.1% of those affected were younger than 13 years old. Toxic agents involved in the incidents were, in descending order, agrochemicals (42.4%), household chemicals (22.1%), carbon monoxide (20.0%), snakebites (14.1%), and food poisoning (1.4%). There was a statistically significant difference with regard to gender, females were more victims of poisoning by snake bites (25.0% vs. 9.7%) and food poisoning (2.5% vs. 1.0%), while males were more affected by carbon monoxide (25.5% vs. 6.3%). Moreover, 61.2% patients spent less than 2 days in hospital, the mean length of stay was 2.1 days, with a range of 1 to 26 days. The overall case fatality rate was 1.4%; of those who died, 75% were males, and the toxic agents responsible for the death were alcohol (50%), carbon monoxide (25%), and organophosphate (25%).

CONCLUSION

Acute poisoning involved more men, who spent more than 2 days being hospitalized, and resulted in a case fatality rate of 1.4% due to alcohol, carbon monoxide, and organophosphates. These findings suggest that further studies are warranted in order to understand the motivation(s) for this emerging problem, and plan appropriate interventions.

摘要

背景

本研究旨在描述乌干达坎帕拉两家医院收治的急性中毒病例特征。

研究设计

对2005年1月至2005年6月期间收治于这两家医院的所有病例进行回顾性评估。从医院病历中获取的数据包括以下内容:人口统计学特征、有毒物质、住院时间、中毒情况以及受害者的死亡信息。

结果

在总共276例入院治疗的患者中,平均年龄为26.6(±12.2)岁,71.0%为男性。20至29岁年龄组受影响最大(42.8%),而受影响者中仅5.1%年龄小于13岁。事件中涉及的有毒物质按降序排列为:农用化学品(42.4%)、家用化学品(22.1%)、一氧化碳(20.0%)、蛇咬伤(14.1%)和食物中毒(1.4%)。在性别方面存在统计学显著差异,女性更多是蛇咬伤中毒的受害者(25.0%对9.7%)和食物中毒的受害者(2.5%对1.0%),而男性受一氧化碳影响更大(25.5%对6.3%)。此外,61.2%的患者住院时间少于2天,平均住院时间为2.1天,范围为1至26天。总体病死率为1.4%;在死亡者中,75%为男性,导致死亡的有毒物质为酒精(50%)、一氧化碳(25%)和有机磷(25%)。

结论

急性中毒男性患者更多,住院时间超过2天,因酒精、一氧化碳和有机磷导致的病死率为1.4%。这些发现表明有必要进行进一步研究,以了解这一新兴问题的原因,并规划适当的干预措施。

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