Chang Chia-Yau, Chiou Tzeon-Jye, Hsieh Yuh-Lin, Cheng Shin-Nan
Department of Pediatrics, Taipei Veterans General Hospital, National Yang-Ming University, Taiwan.
J Pediatr Hematol Oncol. 2003 Sep;25(9):735-9. doi: 10.1097/00043426-200309000-00012.
Acute leukemia can result in leukemic infiltration of many organs, but leukemic infiltration of the bladder is rare. The authors describe an 8-year-old girl with acute lymphoblastic leukemia who, during marrow relapse, had uncontrollable gross hematuria secondary to leukemic infiltration of the bladder. Cystoscopic biopsy confirmed the diagnosis. Literature review revealed 13 cases of acute leukemia with bladder involvement. Although leukemic infiltration of the bladder is rare, it should be considered in patients with acute leukemia and hematuria. Urine cytology might help detect bladder involvement.
急性白血病可导致白血病细胞浸润许多器官，但膀胱的白血病浸润较为罕见。作者描述了一名8岁患急性淋巴细胞白血病的女孩，在骨髓复发期间，因膀胱白血病浸润出现无法控制的肉眼血尿。膀胱镜活检确诊了该诊断。文献回顾显示有13例急性白血病累及膀胱的病例。虽然膀胱白血病浸润罕见，但对于患有急性白血病和血尿的患者应予以考虑。尿细胞学检查可能有助于检测膀胱是否受累。
