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使用两种不同时间模式的射频消融术治疗腰椎间盘源性疼痛:一项随机试验。

Radiofrequency lesioning using two different time modalities for the treatment of lumbar discogenic pain: a randomized trial.

作者信息

Erçelen Omür, Bulutçu Erhan, Oktenoglu Tunç, Sasani Mehdi, Bozkuş Hakan, Cetin Saryoglu Ali, Ozer Fahir

机构信息

Pain Management Department, VKV American Hospital, Istanbul, Turkey.

出版信息

Spine (Phila Pa 1976). 2003 Sep 1;28(17):1922-7. doi: 10.1097/01.BRS.0000083326.39944.73.

Abstract

STUDY DESIGN

A prospective randomized trial.

OBJECTIVE

To evaluate the efficacy of percutaneous intradiscal radiofrequency thermocoagulation by modifying the duration of heating, using two different time methods, for relieving pain and improving functional disability.

SUMMARY OF BACKGROUND DATA

Lumbar discogenic pain is the major problem in lumbar degenerative disc disease that percutaneous intradiscal radiofrequency thermocoagulation has been suggested for as a nonsurgical invasive treatment technique for lumbar discogenic pain. In a previous controlled study, this method was found to be ineffective with 8 weeks of follow-up.

MATERIALS AND METHODS

Sixty patients with chronic low back pain were selected for provocative discography to diagnose the discogenic pain and to locate the discs to be treated. From this group, 39 patients were randomly selected and divided into two groups. In the first group, treatment was performed for 120 seconds, and in the second group for 360 seconds, both at 80C. Patients were assessed with a visual analogue scale for pain relief and functional improvement. Evaluations were performed before, immediately after treatment, at 1 and 2 weeks, and at 1, 3, and 6 months after the procedure.

RESULTS

A total of 39 patients with positive provocative discographies were found to eligible for the study. There were no statistical differences in pain relief and functional improvement between two groups (P > 0.05). The immediate, 1-week and 2-week, and 1-month visual analogue scale (VAS) scores were decreased significantly in both groups when comparing them with the pretreatment scores (P < 0.05). However, the final values after 6 months were similar to those measured at the beginning of the study (P > 0.05).

CONCLUSION

Percutaneous intradiscal radiofrequency thermocoagulation has been suggested and performed to relieve discogenic pain. In the previous controlled study, no effective pain relief has been obtained. In this study, the authors increased the duration of radiofrequency thermocoagulation to improve the effectiveness of this method. Yet, the authors have not found any significant differences between the application of lesioning at two different times in percutaneous intradiscal radiofrequency thermocoagulation.

摘要

研究设计

一项前瞻性随机试验。

目的

通过采用两种不同的时间方法改变加热持续时间,评估经皮椎间盘内射频热凝术缓解疼痛和改善功能障碍的疗效。

背景资料总结

腰椎间盘源性疼痛是腰椎退行性椎间盘疾病的主要问题,经皮椎间盘内射频热凝术已被提议作为一种用于治疗腰椎间盘源性疼痛的非手术侵入性治疗技术。在之前的一项对照研究中,随访8周时发现该方法无效。

材料与方法

选取60例慢性下腰痛患者进行激发性椎间盘造影,以诊断椎间盘源性疼痛并确定待治疗的椎间盘。从该组中随机选取39例患者并分为两组。第一组在80℃下治疗120秒,第二组在80℃下治疗360秒。采用视觉模拟量表评估患者的疼痛缓解情况和功能改善情况。在治疗前、治疗后即刻、1周和2周以及治疗后1、3和6个月进行评估。

结果

共发现39例激发性椎间盘造影阳性的患者符合研究条件。两组在疼痛缓解和功能改善方面无统计学差异(P>0.05)。与治疗前评分相比,两组在治疗后即刻、1周和2周以及1个月时的视觉模拟量表(VAS)评分均显著降低(P<0.05)。然而,6个月后的最终值与研究开始时测量的值相似(P>0.05)。

结论

经皮椎间盘内射频热凝术已被提议并用于缓解椎间盘源性疼痛。在之前的对照研究中,未获得有效的疼痛缓解。在本研究中,作者增加了射频热凝的持续时间以提高该方法的有效性。然而,作者未发现经皮椎间盘内射频热凝术中两种不同时间的损伤应用之间存在任何显著差异。

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