Frydenberg Alexis, Starr Mike
Department of General Medicine, Royal Children's Hospital, Melbourne, Victoria.
Aust Fam Physician. 2003 Aug;32(8):589-92.
Slapped cheek disease, otherwise known as erythema infectiosum (EI) or 'fifth disease', is a common cause of fever and rash in children.
The clinical features in children, and the implications for pregnant contacts will be discussed in this article.
Erythema infectiosum is usually a mild self limiting illness in children. Patients are unlikely to be infectious after the rash and other symptoms are present, and children do not need to be excluded from school or childcare. Infection in pregnant women under 20 weeks gestation can lead to miscarriage or hydrops, but in 50% of cases the fetus is unaffected. Pregnant women who are IgM positive require appropriate specialist referral and serial ultrasounds.
slapped cheek disease，也称为传染性红斑（EI）或“第五病”，是儿童发热和皮疹的常见原因。
本文将讨论儿童的临床特征以及对孕妇接触者的影响。
传染性红斑在儿童中通常是一种轻度自限性疾病。皮疹和其他症状出现后，患者不太可能具有传染性，儿童无需被排除在学校或托儿所之外。妊娠20周以下的孕妇感染可导致流产或水肿，但50%的病例中胎儿不受影响。IgM阳性的孕妇需要适当的专科转诊和系列超声检查。
