Wei Wei, Shen Keng
Department of Obstetric and Gynecology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2003 Aug;25(4):484-6.
While photodynamic therapy is applied on neoplasm, photosensitisers tend to accumulate in neoplastic tissues. With appropriate wavelength light, it causes photochemical reaction and destructs neoplastic tissues. Its better selection for tumor tissue with effective photochemical reaction, and lower side effect make it widespread application in gynecologic oncology. At present, photodynamic therapy has been used in diagnosing and treating lower genital tract carcinoma in situ, and advanced malignant tumor such as vulval and ovarian carcinoma.
当光动力疗法应用于肿瘤时,光敏剂往往会在肿瘤组织中蓄积。在适当波长的光作用下,它会引发光化学反应并破坏肿瘤组织。其对肿瘤组织具有较好的光化学反应选择性,且副作用较低,这使得它在妇科肿瘤学中得到广泛应用。目前,光动力疗法已用于诊断和治疗下生殖道原位癌以及外阴癌和卵巢癌等晚期恶性肿瘤。