Portincasa P, Moschetta A, Colecchia A, Festi D, Palasciano G
Section of Internal Medicine, Department of Internal Medicine and Public Medicine, University Medical School of Bari, Piazza G. Cesare, 70124 Bari, Italy.
Dig Liver Dis. 2003 Jul;35 Suppl 3:S56-61. doi: 10.1016/s1590-8658(03)00096-3.
As real-time ultrasonography is a cheap, noninvasive, relatively easy, validated and reproducible technique, it can be repeated over time to document time-related changes of gallbladder motor function. Ultimately, functional ultrasonography estimates gallbladder shape and volume in fasting state and in response to a test meal (liquid or mixed solid-liquid, provided there is sufficient fat content) or exogenous stimulus (e.g., i.v. cholecystokinin or ceruletide). Although functional ultrasonography of the gallbladder has been mainly used for research purposes in specific referral centres, its simplicity makes such a technique appealing in the clinical setting to assess gallbladder motor function in both health and disease. Indications include the study of healthy subjects and of patients during pathophysiologically relevant conditions; in particular when subjects are at risk for gallbladder stasis and gallstone disease or during gallstone disease when a decision concerning medical dissolution therapy is required.
由于实时超声检查是一种廉价、无创、相对简便、经过验证且可重复的技术，因此可以随时间重复进行，以记录胆囊运动功能随时间的变化。最终，功能性超声检查可估计空腹状态下以及对试餐（液体或固体 - 液体混合餐，前提是有足够的脂肪含量）或外源性刺激（例如静脉注射胆囊收缩素或雨蛙肽）作出反应时胆囊的形状和体积。尽管胆囊功能性超声检查主要在特定的转诊中心用于研究目的，但其简便性使得这种技术在临床环境中对于评估健康和疾病状态下的胆囊运动功能具有吸引力。其适应症包括对健康受试者以及处于病理生理相关状况下的患者进行研究；特别是当受试者有胆囊淤滞和胆结石疾病风险时，或在胆结石疾病期间需要就药物溶石治疗做出决策时。
