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2型糖尿病的患病率、发病率和死亡率再探讨:荷兰的一项基于人群的前瞻性研究(ZODIAC-1)

Prevalence, incidence and mortality of type 2 diabetes mellitus revisited: a prospective population-based study in The Netherlands (ZODIAC-1).

作者信息

Ubink-Veltmaat L J, Bilo H J G, Groenier K H, Houweling S T, Rischen R O, Meyboom-de Jong B

机构信息

Department of Family Practice, University of Groningen, Groningen.

出版信息

Eur J Epidemiol. 2003;18(8):793-800. doi: 10.1023/a:1025369623365.

DOI:10.1023/a:1025369623365
PMID:12974556
Abstract

BACKGROUND

To present actual data to estimate prevalence, incidence and mortality of known type 2 diabetes mellitus in all age categories in The Netherlands.

METHODS

Prospective population-based study between 1998 and 2000 in The Netherlands. Baseline population of 155,774 patients, registered with 61 general practitioners participating in the Zwolle Outpatient Diabetes project Integrating Available Care (ZODIAC)-study.

RESULTS

Age- and sex-adjusted prevalence of type 2 diabetes was 2.2% at baseline and 2.9% after 2 years of follow-up; for women and men it was 3.1 and 2.7% at follow-up, respectively. Patients aged >70 years account for almost 50% of all type 2 diabetes patients. Age- and sex-adjusted mean annual incidence per 10,000 over 3 years was 22.7 overall; for women 23.1 and for men 22.2. Incidence--even though high--decreases after the age of 70 years. The mortality rate was 47.9/1000 and standardised mortality ratio 1.40. Based on these results, the estimated total number of subjects known with type 2 diabetes was 466,000 for The Netherlands in 2000; the number of patients with newly diagnosed diabetes 36,000.

CONCLUSIONS

Prevalence and incidence rates exceed all estimates regarding known type 2 diabetes for The Netherlands. Elderly patients, aged 70 years and over, account for 50% of the type 2 diabetic population. These results are important for health-care planning.

摘要

背景

提供实际数据以估计荷兰所有年龄组中已知2型糖尿病的患病率、发病率和死亡率。

方法

1998年至2000年在荷兰进行的基于人群的前瞻性研究。基线人群为155,774名患者,由参与兹沃勒门诊糖尿病项目整合现有护理(ZODIAC)研究的61名全科医生登记。

结果

基线时2型糖尿病的年龄和性别调整患病率为2.2%,随访2年后为2.9%;随访时女性和男性分别为3.1%和2.7%。70岁以上的患者占所有2型糖尿病患者的近50%。3年期间每10,000人的年龄和性别调整平均年发病率总体为22.7;女性为23.1,男性为22.2。发病率——尽管很高——在70岁以后下降。死亡率为47.9/1000,标准化死亡率为1.40。根据这些结果,2000年荷兰已知2型糖尿病患者的估计总数为466,000人;新诊断糖尿病患者人数为36,000人。

结论

荷兰2型糖尿病的患病率和发病率超过了所有关于已知2型糖尿病的估计。70岁及以上的老年患者占2型糖尿病患者人群的50%。这些结果对医疗保健规划很重要。

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