Woertgen C, Ullrich O W, Rothoerl R D, Brawanski A
Klinik und Poliklinik für Neurochirurgie, Universität Regensburg, Regensburg, Germany.
Zentralbl Neurochir. 2003;64(3):104-8. doi: 10.1055/s-2003-41880.
Delayed cerebral ischemia (DCI) is an important cause of morbidity and mortality after aneurysmatic subarachnoid hemorrhage (SAH). The severity of SAH, reflected by the amount of blood in the initial CCT, is a well-established predictor of DCI and infarction. The Fisher CT scale is widely used to predict DCI, but recent studies criticised the scale due to the fact that this scale does not differentiate between intracerebral blood clots and intraventricular hemorrhage. Thus Claasen et al. recently proposed a new grading scale to predict DCI. The aim of this study was to compare clinical scales with the CT findings and to verify this newly developed scale in a different population in order to predict DCI.[nl]
We selected from our databank of patients suffering from aneurysmatic SAH 292 cases who had been treated between 1995 and 2000. The data acquisition included clinical data, radiological diagnostic data, the postoperative surgical course as well as a follow-up according to the Glasgow outcome scale.[nl]
83 out of 292 patients (28.5 %) developed ischemic lesions on the CT scans reflecting DCI. The severity of SAH according to the Hunt and Hess grading, the Fisher CT scale and the Claassen CT scale correlated statistically significant to DCI. All three scales showed an increasing odds ratio, but the most consistent increase was demonstrated by the Fisher scale.[nl]
The newly proposed Claassen CT scale provides no additional information and seems not to be superior compared to the well-established Fisher scale to predict DCI.
迟发性脑缺血(DCI)是动脉瘤性蛛网膜下腔出血(SAH)后发病和死亡的重要原因。初始头颅CT(CCT)上的出血量所反映的SAH严重程度,是DCI和梗死的公认预测指标。Fisher CT分级广泛用于预测DCI,但最近的研究批评该分级,因为它没有区分脑内血凝块和脑室内出血。因此,Claasen等人最近提出了一种新的分级方法来预测DCI。本研究的目的是将临床分级与CT表现进行比较,并在不同人群中验证这种新开发的分级方法以预测DCI。
我们从1995年至2000年接受治疗的动脉瘤性SAH患者数据库中选取了292例病例。数据采集包括临床数据、放射学诊断数据、术后手术过程以及根据格拉斯哥预后量表进行的随访。
292例患者中有83例(28.5%)在CT扫描上出现反映DCI的缺血性病变。根据Hunt和Hess分级、Fisher CT分级以及Claassen CT分级的SAH严重程度与DCI在统计学上显著相关。所有三种分级的优势比均呈上升趋势,但Fisher分级显示出最一致的上升。
新提出的Claassen CT分级没有提供额外信息,在预测DCI方面似乎并不优于已确立的Fisher分级。