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心包畸胎瘤合并积水:经胸羊膜分流术成功进行胎儿治疗。

Pericardial teratoma complicated by hydrops: successful fetal therapy by thoracoamniotic shunting.

作者信息

Grebille A G, Mitanchez D, Benachi A, Aubry M C, Houfflin-Debarge V, Vouhé P, Dumez Y, Dommergues M

机构信息

Department of Obstetrics, Hôpital Necker-Enfants Malades and University Paris V, Paris, France.

出版信息

Prenat Diagn. 2003 Sep;23(9):735-9. doi: 10.1002/pd.698.

Abstract

Pericardial teratoma is a potentially curable lesion that may become life threatening when it induces mediastinal compression and fetal hydrops. So far, cases with fetal hydrops have been managed by elective delivery or pericardial needle decompression. We report a case in which pericardial teratoma resulted in fetal hydrops. Following transpleural needling of the fetal pericardium at 29 weeks and 6 days, pericardial effusion decreased but hydrops persisted, while major unilateral pleural effusion appeared. A thoracoamniotic shunt was placed at 30 weeks and 5 days. Hydrops resolved, although incompletely. The baby was delivered at 32 weeks and was operated upon on day 3. This observation suggests that fetal hydrops associated with pericardial teratoma may improve following thoracoamniotic shunting. Fetal therapy may limit the risks of respiratory distress arising from the combined effect of airways compression and lung immaturity.

摘要

心包畸胎瘤是一种潜在可治愈的病变,当它引起纵隔压迫和胎儿水肿时可能危及生命。到目前为止,胎儿水肿的病例通过选择性分娩或心包穿刺减压进行处理。我们报告一例心包畸胎瘤导致胎儿水肿的病例。在孕29周6天时经胸膜穿刺胎儿心包后,心包积液减少但水肿持续存在,同时出现大量单侧胸腔积液。在孕30周5天时放置了胸腔羊膜分流管。水肿虽未完全消退但有所缓解。婴儿在孕32周时分娩,并在出生后第3天接受手术。该观察结果表明,与心包畸胎瘤相关的胎儿水肿在胸腔羊膜分流术后可能改善。胎儿治疗可能会降低因气道压迫和肺不成熟共同作用而产生呼吸窘迫的风险。

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