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[精神疾病中的睡眠障碍。流行病学方面]

[Sleep disorders in psychiatric diseases. Epidemiological aspects].

作者信息

Dealberto M J

机构信息

INSERM, Unité 360, Villejuif.

出版信息

Encephale. 1992 Jul-Aug;18(4):331-40.

PMID:1297583
Abstract

Very few epidemiological surveys have specifically studied relationships between sleep disturbances and psychiatric diseases. In this review, we preferred to use the classification proposed in 1979 by the Association of Sleep Disorders Centers. It includes four main categories: insomnias, excessive sleepiness, troubles of the wake/sleep schedule and parasomnias. Evaluating psychiatric disorders among general populations is easier owing to DSM III and DSM III-R criteria, but there are not equivalent criteria in evaluating sleep disorders. It is almost impossible to realize polysomnographic recordings in large samples, therefore sleep disorders are to be detected by questionnaires. It has been shown that there is a good correlation between self-reports and polysomnographic recordings among clinical and general samples. The prevalence of insomnia, defined as difficulties of initiating and maintaining sleep, is estimated between 9 and 31%. It is higher among women, elderly people, separated and divorced subjects, and low educational levels' groups. It has to be noticed that polysomnographic records of some subjective insomniacs are not different from those of good sleepers, sleep latency excepted. These subjective (and not objective) insomniacs have high scores in anxiety scale, depression scale, or psychologic distress. Insomnia is more frequently noted amongst subjects with psychiatric diagnoses, especially major depressive disorders and anxiety disorders. Depressive disorders are present in 21-40% of insomniacs versus 0-1% of non-insomniacs, and anxiety disorders in 13-24% of insomniacs versus 3-10% of non-insomniacs. In depressive disorders, sleep alterations are frequently noted: they are difficulties of initiating and maintaining sleep, decreasing proportion of slow-wave sleep, decreasing time of REM (rapid eye movement) sleep and REM sleep latency, and increasing density of REM sleep. Of these modifications, the last two ones seem to be specific for depression. The relationships between sleep, aging and depression are more complex than previously noted. For example, differences between depressed and non-depressed subjects depend on the age of the population. The prevalence of hypersomnia is lower than the insomnia's. It varies between 2 and 4%. It is more frequently noted among young people, and never married subjects. Two specific aetiologies must be looked for: sleep apnea syndrome and narcolepsy. These diagnoses are respectively found in 45% and 24% of hypersomniacs examined in American Sleep Centers. Hypersomnias are objectived by the Multiple Sleep Latency Test, which measures the physiologic sleep tendency.(ABSTRACT TRUNCATED AT 400 WORDS)

摘要

很少有流行病学调查专门研究睡眠障碍与精神疾病之间的关系。在本综述中,我们倾向于采用睡眠障碍中心协会1979年提出的分类方法。它包括四个主要类别:失眠症、过度嗜睡、睡眠/觉醒节律障碍和异态睡眠。由于有《精神疾病诊断与统计手册》第三版(DSM III)和第三版修订本(DSM III-R)的标准,在普通人群中评估精神疾病比较容易,但在评估睡眠障碍方面却没有等效的标准。要在大样本中进行多导睡眠图记录几乎是不可能的,因此睡眠障碍需通过问卷来检测。研究表明,在临床样本和普通样本中,自我报告与多导睡眠图记录之间存在良好的相关性。失眠的患病率,即入睡和维持睡眠困难的情况,估计在9%至31%之间。在女性、老年人、分居和离婚者以及低教育水平群体中患病率更高。必须注意的是,一些主观失眠者的多导睡眠图记录与良好睡眠者的记录并无差异,除了睡眠潜伏期。这些主观(而非客观)失眠者在焦虑量表、抑郁量表或心理困扰方面得分较高。失眠在患有精神疾病诊断的人群中更为常见,尤其是重度抑郁症和焦虑症。抑郁症在21%至40%的失眠者中存在,而非失眠者中为0%至1%;焦虑症在13%至24%的失眠者中存在,而非失眠者中为3%至10%。在抑郁症中,睡眠改变很常见:包括入睡和维持睡眠困难、慢波睡眠比例降低、快速眼动(REM)睡眠和REM睡眠潜伏期时间减少,以及REM睡眠密度增加。在这些改变中,后两项似乎是抑郁症所特有的。睡眠、衰老和抑郁症之间的关系比之前认为的更为复杂。例如,抑郁和非抑郁受试者之间的差异取决于人群的年龄。嗜睡症的患病率低于失眠症。其患病率在2%至4%之间变化。在年轻人和未婚者中更常被注意到。必须寻找两种特定的病因:睡眠呼吸暂停综合征和发作性睡病。在美国睡眠中心接受检查的嗜睡症患者中,分别有45%和24%被诊断为此病。嗜睡症通过多次睡眠潜伏期试验来客观判定,该试验测量生理睡眠倾向。(摘要截取自400字)

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