Dolenc L, Besset A, Billiard M
Hopital Gui-de-Chauliac, Montpellier, France.
Pflugers Arch. 1996;431(6 Suppl 2):R303-4. doi: 10.1007/BF02346389.
Polysomnographic studies in hypersomniac patients with mood disorders are rare. Previous studies investigated patients with a severe mood disorder, but our study was done in patients with dysthymia, who complained of sleepiness. Mean sleep latency test (MSLT) and continuous polysomnographic recording (CPR) were done in 12 dysthymic patients, in comparison with 12 idiopathic hypersomnia patients, and 12 normal controls. In dysthymic patients mean sleep latency on the MSLT (13 +/- 1) was normal, and when CPR was done during 24 hours, no hypersomnia was found (553 +/- 24). Dysthymic patients showed an abnormal macrostructure of sleep (characterised by an excess of sleep stage I and a decrease of stages 3 and 4), which could be related to their complaint of hypersomnia.
针对患有情绪障碍的发作性睡病患者的多导睡眠图研究很少见。以往的研究调查的是患有严重情绪障碍的患者,但我们的研究针对的是主诉嗜睡的心境恶劣障碍患者。对12名心境恶劣障碍患者、12名特发性发作性睡病患者和12名正常对照者进行了平均睡眠潜伏期测试(MSLT)和连续多导睡眠图记录(CPR)。心境恶劣障碍患者的MSLT平均睡眠潜伏期(13±1)正常,在24小时内进行CPR时,未发现发作性睡病(553±24)。心境恶劣障碍患者表现出睡眠宏观结构异常(特征为睡眠I期过多,3期和4期减少),这可能与他们的嗜睡主诉有关。