通过CpG甲基化实现的转录抑制
Transcriptional repression by methylation of CpG.
作者信息
Meehan R, Lewis J, Cross S, Nan X, Jeppesen P, Bird A
机构信息
Institute of Cell and Molecular Biology, University of Edinburgh, UK.
出版信息
J Cell Sci Suppl. 1992;16:9-14. doi: 10.1242/jcs.1992.supplement_16.2.
Abstract
Methylated DNA in mammals is associated with transcriptional repression and nuclease resistant chromatin. In this review we discuss how these effects may be mediated by proteins that bind to methylated DNA.
摘要
哺乳动物中的甲基化DNA与转录抑制和核酸酶抗性染色质相关。在本综述中，我们讨论了这些效应可能如何由与甲基化DNA结合的蛋白质介导。
Zotero 插件