Shimoyama M, Tsuchiya M
Department of Biochemistry, Shimane Medical University, Izumo, Japan.
J Nutr Sci Vitaminol (Tokyo). 1992;Spec No:271-4. doi: 10.3177/jnsv.38.special_271.
We investigated vertebrate arginine-specific ADP-ribosyltransferases and target proteins for the enzyme. ADP-ribosyltransferase found in each organelle ADP-ribosylated preferentially an endogenous acceptor protein co-localized with the enzyme. We propose that the ADP-ribosylation of tissue-specific target protein by the endogenous ADP-ribosyltransferase may participate in the regulation of cellular processes, including signal transduction.
