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[一名曾患亚急性甲状腺炎患者的急性化脓性甲状腺炎]

[Acute suppurative thyroiditis in a patient with prior subacute thyroiditis].

作者信息

Pantaleoni M, Velardo A, Smerieri A, Toschi E, Zizzo G, Marrama P

机构信息

Cattedra di Endocrinologia, Policlinico, Università degli Studi di Modena.

出版信息

Minerva Endocrinol. 1992 Jul-Sep;17(3):133-6.

PMID:1298872
Abstract

Acute suppurative thyroiditis is an uncommon thyroid disorder usually caused by bacterial infection. The most common route of infection is a fistula that originates from the fundus of the pyriform sinus. Pre-existing thyroid disease, most commonly nodular goiter, has been reported to be present in acute suppurative thyroiditis. A 44 year old man presented a subacute thyroiditis, resolved by nonsteroidal antiinflammatory treatment. One year later, the patient abruptly complained of fever and painful swelling in the thyroid region. A relapse subacute thyroiditis was diagnosed and prednisone treatment was started. A few days later owing to a worsening of the pain and of the clinical features the patient was referred to our department. He presented dysphagia and he was feverish, the overlying skin of the neck swelling was erythematous and warm. There was a neutrophilia (83.7%). Plasma FT4, FT3 and TSH were normal. Anterior neck region ultrasonography showed an enlargement of the left thyroid lobe with poorly defined shapes and inhomogeneous parenchyma while the right lobe of the gland was normal. The 131-I thyroid scan showed a large cold area in the upper part of the left thyroid lobe and preserved radionuclide uptake in the residual parenchyma. The RAIU was normal. We diagnosed acute suppurative thyroiditis and started antibiotics treatment. The day after the patient was still feverish and he gave out from the mouth a great quantity of sero-purulent material with a swelling reduction and improvement of the neck pain. Barium swallow examination did not show any fistula in the cervical esophagus. The fistula opening was demonstrated by indirect laryngoscopy in the postero-lateral side of hypopharynx.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

急性化脓性甲状腺炎是一种罕见的甲状腺疾病,通常由细菌感染引起。最常见的感染途径是源于梨状窝底部的瘘管。据报道,急性化脓性甲状腺炎患者中存在既往甲状腺疾病,最常见的是结节性甲状腺肿。一名44岁男性曾患亚急性甲状腺炎,经非甾体抗炎治疗后痊愈。一年后,患者突然出现发热和甲状腺区域疼痛性肿胀。诊断为亚急性甲状腺炎复发,并开始使用泼尼松治疗。几天后,由于疼痛和临床症状加重,患者被转诊至我科。他出现吞咽困难,发热,颈部肿胀上方的皮肤发红且发热。存在中性粒细胞增多(83.7%)。血浆游离甲状腺素(FT4)、游离三碘甲状腺原氨酸(FT3)和促甲状腺激素(TSH)正常。颈部前方区域超声检查显示左甲状腺叶增大,形态不清,实质不均匀,而右叶正常。碘-131甲状腺扫描显示左甲状腺叶上部有一个大的冷区,残余实质内放射性核素摄取保留。甲状腺摄碘率正常。我们诊断为急性化脓性甲状腺炎并开始使用抗生素治疗。第二天患者仍发热,口腔排出大量浆液脓性物质,肿胀减轻,颈部疼痛改善。吞钡检查未显示颈段食管有任何瘘管。间接喉镜检查显示下咽后外侧有瘘口。(摘要截断于250字)

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