Guliar S A, Il'in V N, Moiseenko E V, Dmitruk A I, Fedorchenko V I, Evtushenko A L, Boltychev I R, Maksimov V P
Aviakosm Ekolog Med. 1992 Jan-Feb;26(1):20-4.
Main trace posthyperbaric and postdecompression responses to respiration, circulation and oxygen profiles, dynamics of their reduction in 99 aquanauts at pressure of 46 kgs/cm2 (0.46 mPa) during 14-30 day period have been studied. The respiratory changes were found to be characterized by: ventilatory function disorders which followed the obstructive-restrictive pattern; discoordination of ventilation regulation and slowing down of respiratory gas transport through aerohematic barrier. The hemodynamic shifts have been manifested as cardiac rhythm instability, heart pump function followed by decreased cardiac contractions on exercise exposures. The economy and efficiency of body oxygen profiles in a respiration loop become lower than that in hemodynamic loop. The rate of the alveolar oxygen supply is decreased to the levels lower than the rates of oxygen supply by arterial and mixed venous blood. The long-term functional rearrangement of respiratory gas transport followed by the phase changes combined with the specific and nonspecific reactions persisting over a period of 30-60 days and more longer after decompression, is existed.
研究了99名潜水员在46千克/平方厘米（0.46兆帕）压力下14至30天期间，高压后和减压后对呼吸、循环及氧分布的主要微量反应，以及这些反应减弱的动态变化。发现呼吸变化的特征为：通气功能障碍呈阻塞性-限制性模式；通气调节失调，呼吸气体通过气血屏障的传输减慢。血液动力学变化表现为心律不稳定，心脏泵血功能在运动暴露后心脏收缩减弱。呼吸回路中身体氧分布的经济性和效率低于血液动力学回路。肺泡氧供应速率降至低于动脉血和混合静脉血供氧速率的水平。呼吸气体传输存在长期功能重排，随后是阶段变化，伴有减压后持续30至60天及更长时间的特异性和非特异性反应。
