Jugie M, Marsot-Dupuch K, Chabolle F, Raveau V, Levy C, Brocheriou C, Tubiana J M
Service de Radiologie, Hôpital Saint-Antoine, Paris.
Ann Radiol (Paris). 1992;35(6):477-82.
Olfactory neuroblastoma, a nerve tumour arising in the olfactory mucosa, is a relatively easy diagnosis in the case of a mass centered around the cribriform plate. It is more difficult to diagnose in its exceptional ectopic forms (maxillary sinus) in the absence of any cytological and histochemical arguments (fibrils, olfactory rosettes). Its local malignancy is variable with a 42% 5-year survival for stage C and metastases in 30% of cases (principally cervical nodes, bone and liver). The role of imaging is to define the criteria of a mass syndrome and to perform the preoperative staging in a case of apparently simple sinus obstruction.
嗅神经母细胞瘤是一种起源于嗅黏膜的神经肿瘤，对于以筛板为中心的肿块来说，诊断相对容易。在没有任何细胞学和组织化学依据（如纤维、嗅神经节细胞团）的情况下，其罕见的异位形式（上颌窦）则更难诊断。其局部恶性程度各不相同，C期患者的5年生存率为42%，30%的病例会发生转移（主要是颈部淋巴结、骨骼和肝脏转移）。影像学检查的作用是确定肿块综合征的标准，并在明显单纯性鼻窦阻塞的病例中进行术前分期。
