鬼笔环肽诱导大鼠肝细胞内肌动蛋白丝的增殖。通过电子显微镜和免疫荧光进行可视化观察。
Phalloidin-induced proliferation of actin filaments within rat hepatocytes. Visualisation by electron microscopy and immunofluorescence.
作者信息
Agostini B, Govindan V M, Hofmann W, Wieland T
出版信息
Z Naturforsch C Biosci. 1975 Nov-Dec;30(6):793-5.
PMID:130011
Abstract
Confirming our previous ultrastructural and biochemical studies, the combined electron microscopy and immunofluorescence investigations show that phalloidin causes a characteristically striking increase of actin filaments within rat hepatocytes. Filaments are localized mainly at the level of special junctional complexes between contiguous cells and around bile canaliculi.
摘要
电子显微镜和免疫荧光联合研究证实了我们之前的超微结构和生化研究结果，表明鬼笔环肽可使大鼠肝细胞内的肌动蛋白丝显著增加。这些丝主要定位于相邻细胞间特殊连接复合体水平以及胆小管周围。
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