红斑狼疮伴急性肝损伤并发弥散性血管内凝血

Disseminated intravascular coagulation in lupus erythematosus with acute liver damage.

作者信息

Shimamoto Y, Sano M, Kaneda S, Tsunada S, Yamamoto K, Yamaguchi M

机构信息

Department of Internal Medicine, Saga Medical School, Japan.

出版信息

Intern Med. 1992 Dec;31(12):1392-5. doi: 10.2169/internalmedicine.31.1392.

DOI:10.2169/internalmedicine.31.1392

PMID:1300175

Abstract

A case of disseminated intravascular coagulation (DIC) in a patient with systemic lupus erythematosus (SLE) with acute liver dysfunction is described. A 37-year-old man with SLE developed acute DIC and marked liver damage after fracture of the right clavicle and pharyngitis. Treatment with high-dose steroids, heparin, antithrombin III, gabexate mesilate, and antibiotics resulted in prompt improvement. The recovery of an SLE patient after acute DIC and marked liver damage is considered very rare. We report here such a case and discuss the previous reports.

摘要

本文描述了一例系统性红斑狼疮（SLE）患者并发急性肝功能不全伴弥散性血管内凝血（DIC）的病例。一名37岁的SLE男性患者在右锁骨骨折和咽炎后发生急性DIC和严重肝损伤。采用大剂量类固醇、肝素、抗凝血酶III、甲磺酸加贝酯和抗生素治疗后病情迅速好转。SLE患者在急性DIC和严重肝损伤后康复的情况被认为非常罕见。我们在此报告这样一例病例并讨论既往报道。