Gómez-Ulla F, Malvar A, Parafita M, Polo P, Seoane I
Department of Ophthalmology, Hospital General de Galicia, University of Santiago, Spain.
Optom Vis Sci. 1992 Dec;69(12):986-90. doi: 10.1097/00006324-199212000-00013.
One hundred oral fluorescein angiographic explorations were performed in 85 patients of both sexes, mean age 55.57 years, and range 8 to 77 years. Fluorescein was administered as one 250-mg (15 patients) or 500-mg (70 patients) capsule per 15 kg of body weight. In 15 fasting and 15 postprandial patients administered 500-mg capsules, no significant differences by group were found between fluorescein plasma levels. Fundus fluorescence under slitlamp illumination was poor for patients receiving the lower dosage of fluorescein, whereas at the higher dosage it was visible in all but one patient. The best filters were found to be a Kodak-Wratten 47A for the excitation filter and Kodak-Wratten 8 for the barrier filter. With a conventional fundus camera and fluorescein angiography filters, good photographs were achieved in all cases. The integrity of the blood-retina barriers was explored for various chorioretinal pathologies.
对85名年龄在8至77岁之间（平均年龄55.57岁）的男女患者进行了100次口服荧光素血管造影检查。荧光素的给药剂量为每15千克体重服用一粒250毫克胶囊（15例患者）或500毫克胶囊（70例患者）。在15名空腹和15名餐后服用500毫克胶囊的患者中，荧光素血浆水平在两组之间未发现显著差异。接受较低剂量荧光素的患者在裂隙灯照明下眼底荧光较差，而在较高剂量时，除一名患者外，其他患者均可见眼底荧光。发现最佳滤光片为用于激发滤光片的柯达 - 瓦特恩47A和用于阻挡滤光片的柯达 - 瓦特恩8。使用传统眼底相机和荧光素血管造影滤光片，所有病例均获得了良好的照片。针对各种脉络膜视网膜病变对血视网膜屏障的完整性进行了研究。
