Hahn H J, Iglesias J, Flenker H, Kreuzer G
Frauenklinik im ZKH Reinkenheide Bremerhaven.
Pathol Res Pract. 1992 Dec;188(8):1091-4; discussion 1094-7. doi: 10.1016/S0344-0338(11)81258-6.
The granular cell tumor (GCT) represents a rare but important lesion in the differential diagnosis of breast tumors. Since this generally benign tumor may be misdiagnosed as malignant in clinical investigation, mammography, sonography, and even in frozen sections, a preoperative diagnosis is of utmost importance. Two cases illustrate that fine needle aspiration cytology (FNAC) may be the method of choice in achieving a correct preoperative diagnosis. The histogenesis of GCT is examined by means of immunohistochemical stainings. The results confirm that this tumor arises from the peripheral nerve tissue. Most likely the Schwann cells and not the nerve cells constitute the origin of GCT.
颗粒细胞瘤（GCT）是乳腺肿瘤鉴别诊断中一种罕见但重要的病变。由于这种通常为良性的肿瘤在临床检查、乳腺X线摄影、超声检查甚至冰冻切片中都可能被误诊为恶性，因此术前诊断至关重要。两个病例表明，细针穿刺细胞学检查（FNAC）可能是实现正确术前诊断的首选方法。通过免疫组织化学染色检查GCT的组织发生。结果证实，这种肿瘤起源于周围神经组织。GCT最有可能起源于施万细胞而非神经细胞。
