Zimmer K
Katedra i Klinika Chirurgii Urazowej AM, Wrocławiu.
Polim Med. 1992;22(3):83-8.
Successful application of the Septopal in treatment of osteomyelitis has created the demand for this form of drug available for implantation into the small operation field, e.c. in the hand. The Chair and Clinic for Traumatology of the Medical Academy in Wrocław has been chosen to cooperate in the clinical trial on application of the Septopal-minichains in surgery of hand. There were 76 patients treated with the Mini-Septopal implantation. In 18 cases the osteomyelitis or active bacterial soft tissue infection gave indications for this type of treatment. In 58 cases Mini-Septopal was implanted because of high risk of infection in contaminated wounds. In both groups bacteriological examinations have been performed and statistical study revealed successful results even in primary resistant for gentamicin bacteries. Very good results of treatment let us estimate very high the usefulness of Mini-Septopal in bone and soft-tissue infections treatment, if the proper surgical procedures are performed to clean the focus of infection.
Septopal在骨髓炎治疗中的成功应用，引发了对这种可植入小手术区域（如手部）的药物剂型的需求。弗罗茨瓦夫医学院创伤学主席及诊所被选中参与Septopal - 微型链在手部手术中应用的临床试验。76例患者接受了Mini - Septopal植入治疗。其中18例骨髓炎或活动性细菌性软组织感染患者适合此类治疗。另外58例因污染伤口感染风险高而植入Mini - Septopal。两组均进行了细菌学检查，统计研究表明，即便对于庆大霉素原发性耐药菌，治疗效果也很成功。如果采取适当的外科手术清理感染病灶，治疗效果良好，这让我们高度评价Mini - Septopal在骨与软组织感染治疗中的效用。
