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[男性乳腺增生症患者和男性乳腺癌中β-酪蛋白基因表达的测定及激素稳态评估]

[The determination of beta-casein gene expression and the assessment of hormonal homeostasis in gynecomastia patients and in breast cancer in men].

作者信息

Ganina K P, Liubimova Iu Iu, Tarutinov V I, Topchiĭ V B, Fedorova L V

出版信息

Vopr Onkol. 1992;38(6):694-9.

PMID:1300768
Abstract

beta-Casein genes expression in breast epithelium was studied in male patients with various forms of gynecomastia and cancer. Blood serum levels of pituitary, sex and glucocorticoid hormones were assayed in 29 patients with gynecomastia and 22 cases of breast cancer, and in 25 of them beta-casein genes expression was evaluated additionally. Activation of the above genes was established in the tissues studied. Their level proved to be in a correlation with that of prolactin.

摘要

在患有各种形式男性乳房发育症和癌症的男性患者中,研究了乳腺上皮中β-酪蛋白基因的表达。对29例男性乳房发育症患者和22例乳腺癌患者的血清垂体、性激素和糖皮质激素水平进行了检测,其中25例还额外评估了β-酪蛋白基因的表达。在所研究的组织中发现了上述基因的激活。其水平与催乳素水平相关。

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