Zhou C W
Cancer Hospital, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Zhong Liu Za Zhi. 1992 Mar;14(2):127-8.
Among 11,821 cases of esophageal carcinoma treated in a 32 year period, 7 were found to be associated with achalasia (0.059%). Five cases were proved by biopsy or cytology and 2 were diagnosed by esophagograms. There were 4 men and 3 women. The age ranged from 30-54 years with a median of 38. The age was younger than that of esophageal carcinoma unassociated with achalasia. Duration of achalasia was from 7 to 20 years. Three patients died within 1 year and 1 died 17 months after diagnosis. Three were lost to follow-up. The presenting symptoms were aggravating dysphagia in 4; and hoarseness, dyspnea and bloody regurgitation in the other two. Patients with achalasia should be treated energetically in the early stage. Double contrast esophagography and esophagoscopy should be done carefully during the followup. Preparation of the esophagus is most important when performing the X-ray examination of the esophagus.
在32年期间治疗的11821例食管癌病例中,发现7例与贲门失弛缓症相关(0.059%)。5例经活检或细胞学检查证实,2例经食管造影诊断。男性4例,女性3例。年龄范围为30 - 54岁,中位数为38岁。该年龄低于与贲门失弛缓症无关的食管癌患者。贲门失弛缓症病程为7至20年。3例患者在1年内死亡,1例在诊断后17个月死亡。3例失访。主要症状为4例吞咽困难加重;另外2例为声音嘶哑、呼吸困难和血性反流。贲门失弛缓症患者应在早期积极治疗。随访期间应仔细进行双重对比食管造影和食管镜检查。进行食管X线检查时,食管准备最为重要。