Rodier J F, Janser J C, Rodier D
Département de Chirurgie Oncologique, Porte de l'Hôpital, Strasbourg.
Ann Chir. 1992;46(10):932-5.
Ovarian metastases occur in the course of colorectal adenocarcinomas on 3 to 14% of cases. They are bilateral in 50-70% of cases and frequently occult (6 to 25%) and constitute a factor of poor short-term prognosis (median survival: 18 months). After analysing the features of ovarian metastases from colorectal cancers, the authors discuss the current place of prophylactic bilateral oophorectomy in terms of its indications and results. Although this procedure should clearly be performed routinely in postmenopausal patients, it is more controversial in women of reproductive age who, according to some authors, nevertheless constitute a group at high risk of ovarian metastases. The contribution of this prophylactic oophorectomy to the improvement in the prognosis of colorectal neoplasms has not been statistically established to date and needs to be demonstrated by means of prospective studies.
卵巢转移瘤发生于3%至14%的结直肠癌病例中。其中50%至70%为双侧性，且常为隐匿性（6%至25%），是短期预后不良的一个因素（中位生存期：18个月）。在分析了结直肠癌卵巢转移瘤的特征后，作者从适应证和结果方面讨论了预防性双侧卵巢切除术目前的地位。尽管该手术在绝经后患者中显然应常规进行，但在育龄女性中更具争议性，一些作者认为她们仍是卵巢转移的高危人群。目前尚无统计学证据表明这种预防性卵巢切除术对改善结直肠肿瘤的预后有帮助，需要通过前瞻性研究来证实。
