Prunet D, Lehur P A, Guiberteau-Canfrère V, Thébaud Y, Litoux P, Le Borgne J
Clinique Chirurgicale II, Hôpital Laënnec, Nantes.
Ann Chir. 1992;46(10):944-6.
We report the case of 41 year-old male patient, in whom multiple and recurrent infrequent cutaneous lesions (sebaceous adenomas) led to suspect the diagnosis of Muir-Torre syndrome. This diagnosis was confirmed when 2 colo-rectal adenocarcinomas were discovered and curatively excised (trans-anal excision, followed by total colectomy). The Muir-Torre syndrome was part of a familial cancer syndrome in this case, as the patient's mother and brother died from colonic cancer before the age of 45. The case-report underlines the diagnostic role of cutaneous lesions in this syndrome, allowing early detection of internal malignancy.
我们报告了一例41岁男性患者的病例，该患者出现多发性且反复出现的罕见皮肤病变（皮脂腺腺瘤），这使得我们怀疑其患有穆尔-托雷综合征。当发现并根治性切除了2例结肠直肠癌（经肛门切除，随后进行全结肠切除术）后，这一诊断得到了证实。在该病例中，穆尔-托雷综合征是一种家族性癌症综合征的一部分，因为患者的母亲和兄弟在45岁之前死于结肠癌。该病例报告强调了皮肤病变在这种综合征中的诊断作用，有助于早期发现内部恶性肿瘤。
