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一名患有穆尔-托雷综合征患者的眼外皮脂腺癌。

Extraocular sebaceous carcinoma in a patient with Muir-Torre syndrome.

作者信息

Harrington Cynthia R, Egbert Barbara M, Swetter Susan M

机构信息

Department of Dermatology, Stanford University Medical Center, Stanford, California 94305, USA.

出版信息

Dermatol Surg. 2004 May;30(5):817-9. doi: 10.1111/j.1524-4725.2004.30224.x.

Abstract

BACKGROUND

Sebaceous carcinoma is a rare, aggressive neoplasm that arises from the adnexal epithelium of sebaceous glands and is commonly associated with Muir-Torre syndrome.

OBJECTIVE

The metastatic potential of extraocular sebaceous carcinoma warrants a thorough evaluation to establish the extent of disease.

METHODS

We describe a 55-year-old man who presented with an asymptomatic abdominal wall mass 3 years after definitive diagnosis of Muir-Torre syndrome.

RESULTS

A biopsy of the surgical specimen revealed sebaceous carcinoma.

CONCLUSION

Dermatologists are crucial to the early recognition and diagnosis of extraocular sebaceous carcinoma. In our patient with documented Muir-Torre syndrome, continued surveillance allowed for prompt recognition and treatment of this associated cutaneous malignancy.

摘要

背景

皮脂腺癌是一种罕见的侵袭性肿瘤,起源于皮脂腺的附属器上皮,通常与穆尔-托里综合征相关。

目的

眼外皮脂腺癌的转移潜能需要进行全面评估以确定疾病范围。

方法

我们描述了一名55岁男性,在确诊穆尔-托里综合征3年后出现无症状的腹壁肿块。

结果

手术标本活检显示为皮脂腺癌。

结论

皮肤科医生对于眼外皮脂腺癌的早期识别和诊断至关重要。在我们这位有记录的穆尔-托里综合征患者中,持续监测使得能够及时识别并治疗这种相关的皮肤恶性肿瘤。

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