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[应用氟塑料分解产物后兔淋巴结的变化]

[Changes in the lymph nodes of rabbits following application of the breakdown products of fluoroplast].

作者信息

Dolgova M A

出版信息

Arkh Anat Gistol Embriol. 1975 Dec;69(12):33-6.

PMID:130096
Abstract

Tracheobronchial, mesenterial and inguinal lymph nodes of 15 mature rabbits which were subjected to inhalation of valatile products of fluoroplast destruction were studied. The action of this drug for 1-40 days activated the reactive centers of follicles. The amount of blasts, plasmic cells, eosinophils, macrophages, lymphocytes increased in regional tracheobronchial and distant mesenterial lymph nodes. The prolonged action during 120 days resulted in decreased blasto- and lymphopoesis in the regional tracheobroncheal lymph nodes, depression of the reticular epithelium, suppression of the phagocytic and plasm cell reactions, decreased nucleic metabolism in the cells. Mesenterial lymph nodes retained their functions. The lymphopoesis in them and nucleic metabolism in the cells were intensified. The blastic, plasmic cell, eosinophilic and mast cell reactions were well pronounced.

摘要

对15只吸入氟塑料破坏挥发性产物的成年兔子的气管支气管、肠系膜和腹股沟淋巴结进行了研究。该药物作用1至40天可激活滤泡的反应中心。在局部气管支气管淋巴结和远处肠系膜淋巴结中,母细胞、浆细胞、嗜酸性粒细胞、巨噬细胞、淋巴细胞的数量增加。作用120天导致局部气管支气管淋巴结中母细胞生成和淋巴细胞生成减少,网状上皮细胞萎缩,吞噬和浆细胞反应受抑制,细胞内核酸代谢降低。肠系膜淋巴结保留了其功能。其中的淋巴细胞生成和细胞内核酸代谢增强。母细胞、浆细胞、嗜酸性粒细胞和肥大细胞反应明显。

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