Minnebaev M M, Mukhutdinova F I
Biull Eksp Biol Med. 1991 Aug;112(8):210-3.
Lymph nodes (mesenteric, popliteal, cervical) of rabbits in fever reaction of different duration have been studied in our work. As a whole morpho-functional changes in lymph nodes in fever reaction indicate the increase of their functional activity: hyperplasia of lymphatic substance with the growth of lymphocytes number and slightly differentiated lymphoid cells in follicles and paracortical zone, hyperplasia of pulposus bands, the signs of macrophagal reaction and plasmatization of lymph nodes are to be observed and all these create prerequisites for the increase of tensity of cellular and humoral immunity. Simultaneously the signs of destruction of cellular elements--lymphocytolysis in the porta tract and the growth of number of PAS-positive cells in the parenchyma of the nodes take place.
我们的研究工作对处于不同发热反应持续时间的家兔的淋巴结(肠系膜、腘窝、颈部)进行了研究。总体而言,发热反应中淋巴结的形态功能变化表明其功能活性增强:淋巴组织增生,滤泡和副皮质区淋巴细胞数量及轻度分化的淋巴样细胞增多,髓索增生,可观察到巨噬细胞反应及淋巴结的浆细胞化迹象,所有这些都为增强细胞免疫和体液免疫强度创造了前提条件。同时,细胞成分破坏的迹象——门区淋巴细胞溶解以及淋巴结实质中PAS阳性细胞数量增加也会出现。