Levashov M M, Lilenko S V, Maslova E P
Aviakosm Ekolog Med. 1992 Mar-Apr;26(2):51-5.
The use of modified, less laborious, easier endured vestibulometric tests made it possible to facilitate diagnosing Menière's disease and neurinomas of the vestibular nerve. Comparison of nystagmometric findings recorded in the same patient during caloric and rotation tests using the diagnostic model of a bithermal test permitted some assumptions to be made in relation to the mechanisms for nystagmogenesis associated with pathologic states in ear labyrinth and vestibular portion craniocerebral (VIII) nerve. It is found that in the majority of Meniere's disease cases (61%) there is a decrease in an intensity of caloric nystagmus induced by Lasix dehydration effect. This phenomenon can be explained by a reduced difference in energy levels of two complexes of vestibular nuclei and, therefore, by an attenuated afferents to peripheral compartment of vestibular system. In neurinoma of aural nerve, the phenomenon of vestibular recruitment (20%) was noted. The diagnostic model of a bithermal test makes it possible to explain an effect of smoothing out the nystagmic responses induced by an intensive stimulus when used a sinusoidal stepwise test. The observed vestibular recruitment results from the severe disorder of one of the afferent inputs due to destruction of induced by tumor pressure.
使用改良的、不那么费力且更容易耐受的前庭功能测试，使得梅尼埃病和前庭神经鞘瘤的诊断更加容易。利用双温试验的诊断模型，对同一患者在冷热试验和旋转试验期间记录的眼震电图结果进行比较，有助于就与耳迷路和颅脑血管（第八）神经病理状态相关的眼震发生机制做出一些假设。研究发现，在大多数梅尼埃病病例（61%）中，速尿脱水效应诱发的冷热眼震强度降低。这种现象可以通过前庭核两个复合体能量水平差异的减小来解释，因此也可以通过前庭系统外周部分传入神经的减弱来解释。在听神经鞘瘤中，观察到前庭反应增强现象（20%）。双温试验的诊断模型能够解释在使用正弦阶梯试验时，强烈刺激诱发的眼震反应趋于平缓的效应。观察到的前庭反应增强是由于肿瘤压迫导致其中一个传入输入严重紊乱所致。
