Pan Y
First Affiliated Hospital of Nanjing Medical College.
Zhonghua Liu Xing Bing Xue Za Zhi. 1992 Aug;13(4):193-6.
The epidemiology of idiopathic cardiomyopathy (ICM) is largely unknown among Chinese population. The purpose of this study was to document the incidence of ICM in the entire residents aged less than 60 years in Nanjing city during the five year period from 1985 to 1989. Using the case registered method it was identified that 275 new cases of ICM collecting from all of the clinically diagnosed outpatients and inpatients in the 14 related hospitals within the city among 2,098,175 residents for years 1985-1989. Over all incidence rate was 2.6 per 100,000 person-years, the age-and sex-adjusted average annual rate being 2.1 per 100,000 directly according to the standardized population of China in 1964 (95% confidence interval 1.9-2.2). This incidence rate was increased from 1.7 per 100,000 in 1985 to 3.3 per 100,000 in 1989 and progressively increasing with aging especially in the groups over 20 years old. Among these 275 patients with ICM, 134 were classified to idiopathic dilated cardiomyopathy (IDCM) and 132 to idiopathic hypertrophic cardiomyopathy (IHCM). Both the average annual incidence rates of IDCM and IHCM were 1.3 per 100,000 and the age-and sex-adjusted rates were 1.1 per 100,000 (95% CI 0.9-1.2) in IDCN and 0.9 per 100,000 (95% CI 0.8-1.0) in IHCM, respectively. The incidence rate of ICM in male was 3.0 significantly higher than 2.2 per 100,000 in female especially in IHCM. The result of this survey is first provided with incidence data of ICM on a broad general population-based study in our country and may be of value in further studying its epidemiology and etiology.
在中国人群中,特发性心肌病(ICM)的流行病学情况很大程度上尚不明确。本研究的目的是记录1985年至1989年这五年间南京市所有年龄小于60岁居民中ICM的发病率。采用病例登记法,在1985 - 1989年期间,从南京市14家相关医院所有临床诊断的门诊和住院患者中,在2098175名居民里确定了275例ICM新发病例。总体发病率为每10万人年2.6例,根据1964年中国标准人口进行年龄和性别调整后的年均发病率直接为每10万人2.1例(95%置信区间1.9 - 2.2)。该发病率从1985年的每10万人1.7例增至1989年的每10万人3.3例,并随年龄增长而逐渐上升,尤其是在20岁以上人群中。在这275例ICM患者中,134例被归类为特发性扩张型心肌病(IDCM),132例为特发性肥厚型心肌病(IHCM)。IDCM和IHCM的年均发病率均为每10万人1.3例,IDCM的年龄和性别调整发病率为每10万人1.1例(95%置信区间0.9 - 1.2),IHCM为每10万人0.9例(95%置信区间0.8 - 1.0)。ICM在男性中的发病率为每10万人3.0例,显著高于女性的每10万人2.2例,在IHCM中尤其明显。本调查结果首次提供了我国基于广泛普通人群研究的ICM发病率数据,可能对进一步研究其流行病学和病因学具有价值。