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[霍乱弧菌抗体试验在霍乱诊断或霍乱弧菌带菌状态判定中的评估]

[The evaluation of the vibriocidal antibody test in establishing a diagnosis of cholera or Vibrio carriage].

作者信息

Savel'ev V N, Efremenko V I, Gnutov I N, Kiseleva T F, Bogdanov I K, Postovoĭ P P, Latypova M S, Abolina T A, Degtiareva S N, Onatskiĭ I I

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1992(11-12):55-7.

PMID:1301665
Abstract

On the basis of the serological survey of cholera patients, vibrio carriers and persons having had contacts with the source or reservoir of Vibrio cholerae the conclusion has been made that the test for the presence of vibriocidal antibodies, together with the bacteriological study of the patient, is of diagnostic importance in the diagnosis of cholera or vibrio carriership. The detection of vibriocidal antibodies, especially in the study of paired sera, permits the detection of cholera cases which have not been bacteriologically confirmed due to various reasons; besides, it makes it possible to exclude the diagnosis of cholera made only on the basis of clinical data. Like bacteriological study, the determination of vibriocidal antibodies must be obligatory for persons hospitalized in a provisory hospital or an isolation ward; it will undoubtedly improve the quality of cholera diagnosis and permit taking timely antiepidemic measures in the focus of infection.

摘要

根据对霍乱患者、弧菌携带者以及与霍乱弧菌来源或宿主有接触者的血清学调查得出结论,杀弧菌抗体检测与患者的细菌学研究相结合,在霍乱或弧菌携带状态的诊断中具有重要的诊断意义。检测杀弧菌抗体,尤其是在双份血清研究中,能够发现因各种原因未得到细菌学确诊的霍乱病例;此外,还能够排除仅基于临床数据做出的霍乱诊断。与细菌学研究一样,对于入住临时医院或隔离病房的人员,检测杀弧菌抗体必须成为一项强制性要求;这无疑将提高霍乱诊断的质量,并有助于在感染源及时采取防疫措施。

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