Gvozdenko N A, Valentsev V E, Rublev B D, Ryzhkov V Iu
Zh Mikrobiol Epidemiol Immunobiol. 1992(11-12):8-10.
The work deals with the results of the study of the viability of Y. pestis strains, isolated from voles in different natural foci of plague, in human normal serum (HNS) and its dependence on the assimilation of ions of exogenic iron. The cultures isolated at the Transcaucasian mountain focus of infection and having no small plasmid pYP were found highly sensitive to HNS. The introduction of the sources of iron, such as hemoglobin or ferritin, into the serum decreased its bactericidal effect.
该研究涉及从鼠疫不同自然疫源地的田鼠中分离出的鼠疫耶尔森菌菌株在人正常血清（HNS）中的生存能力及其对外源铁离子同化作用的依赖性。在外高加索山区感染疫源地分离出的且没有小质粒pYP的培养物对HNS高度敏感。向血清中加入铁源，如血红蛋白或铁蛋白，可降低其杀菌效果。
