Magnano M, Canale G, Lacilla M, Albera R, Orecchia R, Gabriele P
II--Clinica Otorinolaringoiatrica, Università di Torino.
Acta Otorhinolaryngol Ital. 1992 Jul-Aug;12(4):399-405.
The effect of radiation on the vestibular apparatus of animals and man have not been widely investigate. Referred symptoms are disequilibrium and spontaneous nystagmus in animals while histological features are intralabyrinthic haemorrhage, edema of the endolymphatic spaces and alterations of sensory hair cells. A group of 20 patients with head and neck cancer located in different sites (nasal cavity, oropharynx, oral cavity, parotid gland) underwent to vestibular investigations before and 3-6 months after radiation therapy. Ten patients (50%) showed an alteration of the vestibular function of peripheral origin after radiation treatment. Complications appeared from a few weeks up to several months following termination of radiotherapy. The slow development of the lesion permitted central compensation. Few patients had symptoms and vestibular symptomatology was always of secondary importance with respect to the initial pathology.
辐射对动物和人类前庭器官的影响尚未得到广泛研究。动物的相关症状为失衡和自发性眼球震颤，而组织学特征为迷路内出血、内淋巴间隙水肿以及感觉毛细胞改变。一组20例头颈部癌症患者，病变位于不同部位（鼻腔、口咽、口腔、腮腺），在放射治疗前及放疗后3至6个月接受了前庭检查。10例患者（50%）在放射治疗后出现外周性前庭功能改变。并发症在放疗结束后数周直至数月出现。病变发展缓慢，使得中枢能够代偿。少数患者有症状，且相对于初始病变，前庭症状始终处于次要地位。
