Prasad R, Tripathi R P, Mukerji P K, Singh M, Srivastava V M
Department of Tuberculosis, KG's Medical College, Lucknow and Central Drug Research Institute.
Indian J Chest Dis Allied Sci. 1992 Jul-Sep;34(3):123-6.
Adenosine deaminase (ADA) activity in pleural fluids was studied in 47 patients with pleural effusion of different etiology. Patients were divided into two groups: Group I - Tuberculous pleural effusion (21 patients): Group II - Non tuberculous effusion (26 patients) and these included malignant pleural effusion (9 cases), synpneumonic pleural effusion (9 cases) and transudative pleural effusion (8 cases). The mean ADA activity was 64.67 IU/L +/- 21.68 in group I and 6.99 +/- 3.69 in Group II. Increased mean pleural fluid ADA activity in tuberculous pleural effusion was highly significant (p < 0.001) when compared with pleural effusion of non-tuberculous etiology. Based on lowest value of ADA activity found in tuberculous pleural effusion (30 IU/L), the test has a sensitivity and specificity of 1.
对47例不同病因胸腔积液患者的胸腔积液腺苷脱氨酶（ADA）活性进行了研究。患者分为两组：第一组 - 结核性胸腔积液（21例）；第二组 - 非结核性胸腔积液（26例），其中包括恶性胸腔积液（9例）、肺炎旁胸腔积液（9例）和漏出性胸腔积液（8例）。第一组的平均ADA活性为64.67 IU/L±21.68，第二组为6.99±3.69。与非结核病因的胸腔积液相比，结核性胸腔积液中平均胸腔积液ADA活性升高具有高度显著性（p<0.001）。基于结核性胸腔积液中发现的ADA活性最低值（30 IU/L），该检测的敏感性和特异性为1。
