Stickl H
Fortschr Med. 1977 Jan 13;95(2):76-8.
In 1801 the smallpox vaccination has been introduced in Bavaria by order of the Duke Franz Joseph. He appointed a Medical Superintendent, responsible for smallpox vaccinations for the whole country. This was the hour of birth for the Institute, too. The Institute developed quickly to a point of crystallization in the field of prophylactic medicine, research on infectious diseases and social pediatrics. By this Institute the "Retrovaccine" against smallpox was introduced 1856. 1967 -- 1976 an attenuated life smallpox-vaccine (MVA) has been developed. Some years ago the activities of the Institute had been focussed into research of complications after vaccinations and up to date, on the pathogenesis of Multiple Sclerosis. A historical review demonstrates the development of the Institute in the past up to modern activities in research, teaching students and postgraduate education and in medical practice.
1801年，在巴伐利亚公爵弗朗茨·约瑟夫的命令下，天花疫苗被引入。他任命了一位医务主管，负责全国的天花疫苗接种工作。这也是该研究所的诞生之时。该研究所在预防医学、传染病研究和社会儿科学领域迅速发展成为一个核心机构。1856年，该研究所引入了针对天花的“逆转疫苗”。1967年至1976年，一种减毒活天花疫苗（MVA）被研发出来。几年前，该研究所的活动集中在疫苗接种后并发症的研究上，而目前则集中在多发性硬化症的发病机制研究上。一篇历史回顾展示了该研究所从过去到现代在研究、学生教学和研究生教育以及医疗实践方面的发展历程。
