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[从公共卫生服务角度看MVA免疫接种计划的应用]

[Utilization of the MVA-immunization schedule from the view point of the public health service].

作者信息

Weber H G

出版信息

Fortschr Med. 1977 Jun 2;95(21):1381-6.

PMID:17567
Abstract

The world-wide smallpox eradication program sponsored by the WHO has been successful. Furthermore the legislation regarding smallpox vaccination in the Federal Republic of Germany has been given a new form. The place of the previous mass-vaccination has been taken by vaccination of individuals. Under this aspect safe procedures for vaccination are required. Any vaccination used by Public Health Service has to fulfill the following criteria: High protection against the disease without adverse side-effects or risks; it should be simple to administer and applicable under ordinary circumstances. For primary vaccination against smallpox the MVA-vaccination meets these demands entirely. It is reported about own experiences with 700 vaccinations using the attenuated virus "MVA"; complete documentation is given. Not a single complication nor any adverse side-effects have been seen. The Public Health Service has gained great experience in the field of vaccination. It is responsible for the protection of the individual as well as the public, as it is undesirable that there develops and unvaccinated group within the population. The individual claim a complete protection through vaccination which should be absolutely free of any risk.

摘要

由世界卫生组织发起的全球天花根除计划取得了成功。此外,德意志联邦共和国关于天花疫苗接种的立法也有了新形式。以前的大规模疫苗接种已被个体接种所取代。在这方面,需要安全的接种程序。公共卫生服务部门使用的任何疫苗都必须符合以下标准:对疾病有高度防护作用且无不良副作用或风险;易于接种且在普通情况下适用。对于天花的初次接种,改良痘苗病毒安卡拉(MVA)疫苗完全满足这些要求。报告了使用减毒病毒“MVA”进行700次接种的自身经验,并给出了完整记录。未观察到任何并发症或不良副作用。公共卫生服务部门在疫苗接种领域积累了丰富经验。它负责保护个体和公众,因为人群中出现未接种疫苗的群体是不可取的。个体要求通过绝对无任何风险的疫苗接种获得全面保护。

相似文献

1
[Utilization of the MVA-immunization schedule from the view point of the public health service].[从公共卫生服务角度看MVA免疫接种计划的应用]
Fortschr Med. 1977 Jun 2;95(21):1381-6.
2
[MVA vaccination against smallpox: clinical tests with an attenuated live vaccinia virus strain (MVA) (author's transl)].[痘苗病毒安卡拉株(MVA)预防天花的疫苗接种:减毒活痘苗病毒株(MVA)的临床试验(作者译)]
Dtsch Med Wochenschr. 1974 Nov 22;99(47):2386-92. doi: 10.1055/s-0028-1108143.
3
Enhanced immunogenicity and protective effect conferred by vaccination with combinations of modified vaccinia virus Ankara and licensed smallpox vaccine Dryvax in a mouse model.在小鼠模型中,用改良安卡拉痘苗病毒和已获许可的天花疫苗Dryvax联合接种所赋予的增强免疫原性和保护作用。
Virology. 2005 Sep 1;339(2):164-75. doi: 10.1016/j.virol.2005.06.002.
4
[The development of vaccination as demonstrated on the development of the Bavarian State Vaccination Institute in the 19th and 20th centuries].[19世纪和20世纪巴伐利亚州立疫苗接种研究所的发展所展示的疫苗接种发展历程]
Fortschr Med. 1977 Jan 13;95(2):76-8.
5
[Development of a numerically additive combined vaccine against tetanus and smallpox].[一种针对破伤风和天花的数字相加联合疫苗的研发]
Zentralbl Bakteriol Mikrobiol Hyg A. 1985 Apr;259(2):206-18.
6
[Primary vaccination against smallpox after preliminary vaccination with the attenuated vaccinia virus strain MVA and the use of a new "vaccination stamp"].[使用减毒痘苗病毒株MVA进行初步接种后接种天花疫苗及使用新型“接种印章”]
Munch Med Wochenschr. 1973 Aug 31;115(35):1471-3.
7
Modified vaccinia Ankara: potential as an alternative smallpox vaccine.安卡拉改良痘苗病毒:作为替代天花疫苗的潜力。
Clin Infect Dis. 2004 Jun 15;38(12):1749-53. doi: 10.1086/421266. Epub 2004 May 19.
8
[Pro and con smallpox vaccination. 2. Optimal vaccination time and optimal vaccination age].[天花疫苗接种的利弊。2. 最佳接种时间和最佳接种年龄]
Fortschr Med. 1972 May 18;90(15):578-83 concl.
9
[For and against smallpox vaccination. Epidemiological background and its significance for optimal vaccination time and optimal vaccination age].[支持与反对天花疫苗接种。流行病学背景及其对最佳接种时间和最佳接种年龄的意义]
Fortschr Med. 1972 May 11;90(14):533-6.
10
[Our experiences with the 2-stage method of vaccination against smallpox (MVA virus pre-vaccination)].[我们采用两阶段天花疫苗接种方法(痘苗病毒载体疫苗预接种)的经验]
Pediatr Pol. 1976 May;51(5):497-503.

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