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[急性局灶性缺血时脑功能状态的动态变化]

[Dynamics of the functional state of the brain in acute focal ischemia].

作者信息

Gusev E I

出版信息

Patol Fiziol Eksp Ter. 1992 Jul-Aug(4):44-6.

PMID:1303502
Abstract

Complex clinical-neurophysiological investigation of 200 patients with cerebral acute focal ischemia was carried out. It included polymodal monitoring of brain functional activity: monitoring of electroencephalography (EEG), compressed spectral array and toposelective mapping of somatosensory evoked potentials, acoustic short-latency evoked potentials, transcranial cortical electric stimulation, electromyo- and electroneuromyography. The development of acute focal cerebral ischemia was shown to be independent of its location, kind and prognosis, accompanied by functional reorganization of whole brain: its supersegmented specialized motor and sensory functional systems, nonspecific formations of segmental peripheral system. These changes in cerebral functional activity can be found already during first hours of ischemia and they remain generalized during 3-5 days.

摘要

对200例急性局灶性脑缺血患者进行了复杂的临床神经生理学研究。研究包括对脑功能活动的多模态监测:脑电图(EEG)监测、压缩谱阵图以及体感诱发电位、听觉短潜伏期诱发电位的拓扑选择性映射、经颅皮层电刺激、肌电图和神经肌电图。结果显示,急性局灶性脑缺血的发生与其位置、类型和预后无关,同时伴有全脑功能重组:其超节段性的专门运动和感觉功能系统,以及节段性外周系统的非特异性结构。这些脑功能活动的变化在缺血后的最初几个小时内即可发现,并在3至5天内保持全身性。

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