Grabski W, Rozniecki J, Grzegorczyk J
Kliniki Pneumonologii i Alergologii IMW AM, Lodzi.
Pneumonol Alergol Pol. 1992;60(11-12):5-10.
To assess the incidence of the late reaction of the bronchi in patients with atopic asthma the following methods of the provocation with atopic asthma the following methods of the provocation were applied: a) exercise test, b) a 3-minute ventilation with cold air and c) inhalation of the distilled water Disturbances of ventilation were assessed spirographically. An emphasis was also on the activity of NCF in the blood serum following the applied provocation tests. It was found that the late bronchospasm followed the exercise test in about half of the examined patients (48%). It was less frequent after hyperventilation with cold air (33%) and inhalation of the distilled water (38%). Bronchospasm was accompanied by the increase in NCF activity in the blood serum. The late bronchospasm after provocation tests in asthmatics is a real fact, not depending on the accidental ventilation disorders.
为评估特应性哮喘患者支气管迟发反应的发生率,采用了以下特应性哮喘激发方法:a)运动试验,b)冷空气3分钟通气,c)蒸馏水吸入。通过肺量计评估通气障碍。还重点关注了应用激发试验后血清中中性粒细胞趋化因子(NCF)的活性。结果发现,约一半(48%)的受检患者在运动试验后出现迟发性支气管痉挛。在冷空气过度通气后(33%)和蒸馏水吸入后(38%),其发生率较低。支气管痉挛伴有血清中NCF活性增加。哮喘患者激发试验后的迟发性支气管痉挛是一个真实存在的现象,并非取决于偶然的通气障碍。