Zhou X, Yue S, Tan H
Hua Xi Yi Ke Da Xue Xue Bao. 1992 Sep;23(4):389-91.
Five cariogenic bacteria were used to produce a plaque, called artificial plaque, by sequential culture in vitro. The results showed that the artificial plaque is very similar to the natural one in morphology and structure. Artificial plaque may be taken as an excellent model in vitro for the studies on cariogenicity of dental plaque.