Zhou X, Yue S
Hua Xi Yi Ke Da Xue Xue Bao. 1991 Sep;22(3):225-8.
The authors used the cariogenic bacteria isolated from human dental plaque to produce an artificial plaque which can produce carious lesion in vitro. Lesions on human enamel slabs produced by artificial plaque and single bacterium were observed under polarized light microscope and scanning electron microscope. The results showed that the characters of artificial carious lesions are very similar to natural enamel caries. It is very difficult to differentiate them under the microscopes. Compared with the lesions produced by single strain, the destructive fashion observed in lesions produced by artificial plaque is more similar to the changes produced by natural dental plaque.
作者使用从人类牙菌斑中分离出的致龋菌制作了一种人工菌斑,该菌斑可在体外产生龋损。在偏光显微镜和扫描电子显微镜下观察了人工菌斑和单一细菌在人类牙釉质块上产生的损害。结果表明,人工龋损的特征与天然牙釉质龋非常相似。在显微镜下很难区分它们。与单一菌株产生的损害相比,人工菌斑产生的损害中观察到的破坏方式更类似于天然牙菌斑产生的变化。