Collet E, Boulitrop-Morvan C, Dalac S, Camus P, Lambert D
Service de Dermatologie, Hôpital du Bocage, Dijon.
Ann Dermatol Venereol. 1992;119(12):971-4.
Sarcoidosis is seldom associated with Waldenström's macroglobulinaemia. We report the case of a 58-year old woman, 7 years after cutaneous and pulmonary sarcoidosis had begun, developed Waldenström's macroglobulinaemia. Chlorambucil was effective on both diseases. The possibility of reactive sarcoidotic granulomas in neoplastic diseases may cast doubts on the reality of the sarcoidosis-malignant haemopathy association. However, most authors consider that such associations are not fortuitous and can be explained by the immunological abnormalities observed in patients with sarcoidosis.
结节病很少与华氏巨球蛋白血症相关。我们报告一例58岁女性病例，在皮肤和肺部结节病开始7年后，患上了华氏巨球蛋白血症。苯丁酸氮芥对这两种疾病均有效。肿瘤性疾病中出现反应性结节病肉芽肿的可能性可能会让人对结节病与恶性血液病之间关联的真实性产生怀疑。然而，大多数作者认为这种关联并非偶然，可由结节病患者中观察到的免疫异常来解释。
